Drug intelligence / Profile preview

Cranfluxx

Development stage
Unknown
Lead developer
Ruhrpharm
Modality
Small Molecules
Administration
Oral
01

Overview

Cranfluxx is a nutraceutical supplement developed by Ruhrpharm, primarily indicated for the prevention and management of urinary tract infections (UTIs). The active component is cranberry extract, which is rich in proanthocyanidins (PACs). The primary mechanism of action involves inhibiting the adhesion of uropathogenic bacteria, specifically P-fimbriated *Escherichia coli*, to the uroepithelial cells lining the urinary tract. By preventing bacterial attachment, the supplement facilitates the flushing of bacteria during urination, thereby reducing the risk of colonization and subsequent infection. It is marketed as an approved dietary supplement in Germany.

Brand names
Cranfluxx
Other names
Cranberry extract
02

Targets

P fimbriae

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