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Crest 3D White

Development stage: Preclinical
Lead developer: Procter & Gamble
Modality: Small Molecules
Administration: Topical

Overview

**Crest 3D White** is a Procter & Gamble over-the-counter fluoride whitening toothpaste product line. In the referenced head-to-head tooth-whitening study, the comparator was a Crest 3D White toothpaste containing fluoride and no hydrogen peroxide. Sodium fluoride provides anticavity activity by promoting enamel remineralization and increasing resistance to acid-mediated demineralization, while hydrated silica and other polishing agents remove extrinsic surface stains. Product-line variants can differ in whitening ingredients; the comparator formulation should not be conflated with peroxide-containing Crest 3D White variants.

Brand names: Crest 3D WhiteCrest3D WhiteCrest-3D White
Other names: Crest3DWhiteCrest-3DWhiteCrest 3DWhite

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