Drug intelligence / Profile preview

CRIE quadrivalent meningococcal vaccine

Development stage
Preclinical
Lead developer
Central Research Institute of Epidemiology
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular, Subcutaneous
01

Overview

The CRIE quadrivalent meningococcal vaccine is a non-live vaccine candidate developed by the Central Research Institute of Epidemiology (CRIE) in Russia. It is designed to provide active immunity against *Neisseria meningitidis* serogroups A, C, W-135, and Y, which are among the most common causes of invasive meningococcal disease, including meningitis. The vaccine is intended for pediatric use, specifically targeting children who have not previously received a meningococcal vaccine. A clinical trial for children aged 3 to 11 years is scheduled to commence in September 2025 to evaluate the safety and immunogenicity of the formulation.

Other names
Central Research Institute of Epidemiology-Neisseria meningitidis (serogroups A, C, W-135, Y)-non-live vaccine-Meningococcal infection (meningitis)non-live meningococcal vaccinequadrivalent meningococcal vaccine (A, C, W-135, Y)
02

Targets

Group Y CPS (Neisseria meningitidis group Y capsular polysaccharide)

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