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Crocus sativus tepal extract is a botanical preparation derived from the petals (tepals) of the saffron plant, which are typically considered a byproduct of saffron production. This specific cold aqueous extract, developed by the University of Primorska, is being investigated for its acute metabolic effects in individuals with obesity and prediabetes. The extract is rich in bioactive polyphenols, including anthocyanins and flavonoids, which are hypothesized to improve postprandial glycemic control, modulate insulin responses, and potentially increase resting energy expenditure. Clinical evaluation focuses on its ability to mitigate the glycemic spike following a standard carbohydrate-rich meal, offering a potential natural intervention for metabolic health management.
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