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cross-linked sodium hyaluronate gel

Development stage: Phase 3
Lead developer: Changzhou Raj Biological Pharmaceutical
Modality: Nanoparticles → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems, Device-based Delivery → Drug Delivery Systems
Administration: Intrauterine Injection, Intradermal Implant, Intra-articular Injection, Intraocular Injection

Overview

Cross-linked sodium hyaluronate gel is a sterile, transparent gel composed of hyaluronic acid (HA), a naturally occurring polysaccharide, that has been chemically modified through cross-linking. This cross-linking process, often utilizing agents like BDDE, enhances the gel's stability, viscoelastic properties, and resistance to enzymatic degradation, resulting in a longer-lasting product compared to non-cross-linked HA. It is biocompatible and bioresorbable. The gel functions primarily by forming a physical barrier, providing lubrication, and adding volume to tissues. Its applications span various medical fields, including aesthetic medicine for facial tissue augmentation, wrinkle correction, and lip enhancement; ophthalmology for dry eye treatment and as an auxiliary material in surgery; orthopedics for intra-articular injections to treat arthritis and improve joint lubrication; and gynecology for preventing intrauterine adhesions after uterine surgery. Changzhou Raj Biological Pharmaceutical Co., Ltd. is a manufacturer of this product, including the brand "Gong'anKang".

Brand names: SingfillerSingRejuvePureRegen®Gel SinusGong'anKangHai Rui JiGong An Bao
Other names: 交联透明质酸钠凝胶xlHA gelcrosslinked hyaluronan gelauto-crosslinked hyaluronic acid gel

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