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croton heliotropiifolius essential oil
- Development stage
- Preclinical
- Lead developer
- Universidade Federal do Ceará
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Croton heliotropiifolius essential oil is a natural product extracted from the leaves of *Croton heliotropiifolius Kunth*, a plant native to northeastern Brazil. It is a complex mixture of volatile compounds, primarily sesquiterpenes and monoterpenes, including β-caryophyllene, α-pinene, and 1,8-cineole. The oil is being researched by Brazilian academic institutions for its potential as an anticonvulsant, antimicrobial, and anticancer agent. Its anticonvulsant effects are thought to be mediated through the modulation of GABAA and NMDA receptors, specifically by constituents like α-bulnesene and guaiadiene. It is currently in the preclinical research stage.
- Other names
- essential oil of Croton heliotropiifoliusCroton heliotropiifolius Kunth essential oil
02
Targets
BZD site (GABA-A receptor benzodiazepine site)GluR (Glutamate receptors)
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