crude heparin

Crude heparin is a raw active pharmaceutical ingredient (API) and intermediate product manufactured by **Hebei Changshan Biochemical Pharmaceutical Co., Ltd. (HBCS Bio)**. Extracted from porcine intestinal mucosa, it serves as the essential starting material for the production of refined heparin sodium and various low molecular weight heparins (LMWH), such as enoxaparin, nadroparin, and dalteparin. Its mechanism of action involves binding to and potentiating **Antithrombin III (ATIII)**, which subsequently inhibits key serine proteases in the coagulation cascade, primarily **Thrombin (Factor IIa)** and **Factor Xa**. As a crude extract, it is not a finished marketed drug intended for direct clinical administration but is a critical component in the global supply chain for anticoagulant medications used to treat and prevent thrombotic conditions.

Other names

Raw heparinCrude heparin API