Drug intelligence / Profile preview

cryoprecipitated fibrinogen complex

Development stage
Unknown
Lead developer
Cerus Corporation
Modality
Recombinant Proteins and Enzymes
Administration
Intravenous
01

Overview

Cryoprecipitated Fibrinogen Complex is a pathogen-reduced, concentrated source of fibrinogen, von Willebrand factor, Factor VIII, Factor XIII, and fibronectin derived from human plasma. It is manufactured using the INTERCEPT Blood System, which utilizes amotosalen (a photoactive compound) and long-wavelength ultraviolet (UVA) light to inactivate a broad spectrum of viruses, bacteria, and parasites. Developed by Cerus Corporation, it is the first pathogen-reduced fibrinogen concentrate approved by the FDA. It is primarily indicated for the treatment and control of bleeding associated with fibrinogen deficiency, including massive hemorrhage and acquired hypofibrinogenemia, often used in surgical settings such as liver transplantation or cardiac surgery.

Brand names
INTERCEPT Fibrinogen Complex
Other names
Pathogen Reduced Cryoprecipitated Fibrinogen ComplexCryoprecipitate Intercept Fibrinogen Complex

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