Drug intelligence / Profile preview

CS02 + metformin

Development stage
Unknown
Lead developer
Center Laboratories
Modality
Small Molecules
Administration
Oral
01

Overview

CS02 + metformin is an investigational **combination therapy** consisting of the experimental agent CS02 (administered as a tablet) together with a stable dose of metformin, a widely used antihyperglycemic drug. The combination is being evaluated primarily in clinical studies for **type 2 diabetes mellitus**. CS02's mechanism of action and full pharmacology remain undisclosed in public results, but metformin is well characterized as a biguanide acting to decrease hepatic glucose production, increase insulin sensitivity, and enhance peripheral glucose uptake. Combination therapies are commonly used to improve glycemic control in patients who do not achieve adequate control with monotherapy.

02

Targets

COX7C (Cytochrome c oxidase subunit 7C, mitochondrial)CREB-CBP-CRTC2 (cAMP response element-binding protein-CREB-binding protein-CREB-regulated transcription coactivator 2 transcriptional complex)V-ATPase (Vacuolar-type H+-ATPase)ND1 (Mitochondrial electron transport chain complex I)

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