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CS10BR05 is an autologous bone marrow-derived mesenchymal stem cell (MSC) therapy developed by Corestemchemon for the treatment of Multiple System Atrophy (MSA). The therapy involves the isolation and expansion of MSCs from the patient's own bone marrow, which are then administered via intra-arterial injection into the carotid artery. CS10BR05 is designed to exert neuroprotective effects and modulate neuroinflammation, potentially slowing the neurodegenerative process in MSA. It has been evaluated in Phase 1 clinical trials for safety and tolerability, with long-term follow-up studies monitoring efficacy and adverse events.
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