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CS27186 is a small molecule dual inhibitor of Vascular Endothelial Growth Factor Receptor (VEGFR) and Fibroblast Growth Factor Receptor (FGFR), currently under development by Chipscreen NewWay, a subsidiary of Chipscreen Biosciences. By simultaneously targeting the VEGFR and FGFR signaling pathways, the compound is designed to inhibit tumor-associated angiogenesis and suppress tumor cell proliferation and survival. This dual-targeting approach may provide enhanced efficacy and help overcome resistance compared to selective inhibitors of either pathway alone. CS27186 is currently in Phase 1 clinical development for the treatment of various solid tumors.
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