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CT1190B
- Development stage
- Unknown
- Lead developer
- CARsgen Therapeutics
- Modality
- CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Gene Therapies
- Administration
- Intravenous
01
Overview
CT1190B is an investigational autologous chimeric antigen receptor (CAR) T-cell therapy developed by Tongji Hospital (Huazhong University of Science and Technology) for the treatment of relapsed or refractory B-cell non-Hodgkin lymphoma. The therapy involves genetically engineering a patient's own T cells to express a CAR that specifically targets CD19, a protein found on the surface of most B-cell malignancies. Once re-infused into the patient following lymphodepletion, these modified T cells recognize and eliminate CD19-positive lymphoma cells. It is currently being evaluated in a Phase 1 clinical trial focusing on safety, efficacy, and cellular metabolism.
- Other names
- CAR T cells-Tongji Hospital-B-cell non-Hodgkin lymphoma
02
Targets
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