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cta-30x

Development stage: Phase 1
Lead developer: Bioheng Therapeutics
Modality: Gene Addition/Replacement → Gene Therapies, Gene Silencing → Gene Therapies, Gene Editing → Gene Therapies, CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
Administration: Intravenous

Overview

CTA-30X is an allogeneic chimeric antigen receptor T-cell (CAR-T) therapy targeting CD19. It is a universal CAR-T (UCAR-T) product developed by Nanjing Bioheng Biotech for the treatment of CD19-positive B-cell malignancies. The therapy involves gene transference and T lymphocyte replacement to engineer donor-derived T cells that express a CAR specific for the B-lymphocyte antigen CD19. This approach enables off-the-shelf immunotherapy for patients with relapsed or refractory B-cell hematologic malignancies such as acute lymphoblastic leukemia and diffuse large B-cell lymphoma[1][4][5].

Other names: CTA30X cell injectionCTA-30X cell injectionCTA 30X cell injection

Targets

CD19 (B lymphocyte antigen CD19)

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