Drug intelligence / Profile preview

CTA002

Development stage
Preclinical
Lead developer
CTCELLS
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

CTA002 (also known as CTA-02) is an early-stage programmed death-ligand 1 (PD-L1) inhibitor being developed by CTCELLS. It is currently in the discovery phase for the treatment of various neoplasms, as well as skin and musculoskeletal conditions. As a checkpoint inhibitor, CTA002 is designed to block the interaction between PD-L1, often expressed on the surface of tumor cells, and the PD-1 receptor on T cells. By inhibiting this pathway, the drug aims to prevent immune evasion by tumors and restore the ability of the immune system to recognize and eliminate malignant cells.

02

Targets

CD274 (Programmed cell death protein 1 ligand 1)

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