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CTN-012 is a monoclonal antibody drug candidate developed by Centenaire Biosciences. It functions as an antagonist of fibroblast growth factor receptor 3 (FGFR3), targeting this receptor to inhibit its activity. FGFR3 is implicated in the development and progression of certain cancers, particularly bladder cancer. By blocking FGFR3 signaling, CTN-012 aims to disrupt tumor cell proliferation and survival pathways associated with neoplasms and urogenital diseases. As of May 2025, the drug remains in preclinical development for bladder cancer[1].
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