Drug intelligence / Profile preview

CTX-944

Development stage
Preclinical
Lead developer
Pareto Bio
Modality
Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
01

Overview

**CTX-944** is a proprietary live biotherapeutic product (microbial therapeutic) developed by ConsortiaTX for the treatment of food allergies. It is designed as a first-in-kind, allergen-independent therapy that leverages microbiome modulation to reverse allergic responses, building on research into microbial consortia that promote immune tolerance to allergens. The therapy aims to reprogram the gut microbiome to induce desensitization and long-term tolerance, potentially addressing peanut and other food allergies without relying on specific allergen exposure.[3][5]

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