Drug intelligence / Profile preview

cumin seed extract

Development stage
Phase 3
Lead developer
Assiut University
Modality
Small Molecules
Administration
Oral, Topical (vaginal Suppository)
01

Overview

Cumin seed extract is a herbal preparation derived from the seeds of the plant Cuminum cyminum. It is traditionally used in food as a spice and in various traditional medicine systems for its purported health benefits. The main bioactive constituents include cuminaldehyde, γ-terpinene, β-pinene, p-cymene, and other volatile oils[6][9]. Preclinical studies suggest that cumin seed extracts may have hypoglycemic (blood sugar-lowering), antioxidant, lipid-lowering (cholesterol-reducing), antibacterial, antifungal (notably against Candida albicans), and antiaggregatory effects on platelets[1][2][7]. Clinical evidence supporting these uses remains limited; however, there are small clinical trials investigating its use for vulvovaginal candidiasis via vaginal suppositories and as an ingredient in artificial saliva[7]. The mechanism of action is not fully elucidated but may involve inhibition of microbial growth and modulation of metabolic pathways related to lipids and glucose. Cumin seed extracts are generally recognized as safe when used as a spice or flavoring agent.

Other names
Cuminum cyminum extractcumin extractJeera extractZira extract

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