Drug intelligence / Profile preview

cupressus arizonica pollen

Development stage
Phase 2
Lead developer
ALK Abelló
Modality
Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Administration
Intradermal, Intranasal, Subcutaneous, Sublingual
01

Overview

Cupressus arizonica pollen is an allergenic extract derived from the pollen of the Arizona cypress tree. It is used for allergen-specific immunotherapy (AIT) to treat respiratory allergies such as rhinoconjunctivitis and asthma caused by sensitization to cypress pollen. [2] The treatment involves administering gradually increasing doses of the extract to desensitize the immune system, thereby reducing the allergic response upon natural exposure. [11] Companies including ALK-Abelló, LETI Pharma, and Inmunotek are involved in the development, standardization, and clinical evaluation of Cupressus arizonica pollen extracts for both diagnostic and therapeutic purposes. [7, 8] Clinical studies have focused on its tolerability, efficacy, and the standardization of its major allergen, Cup a 1, to ensure product quality and potency. [2, 11] It can be administered via subcutaneous injection or sublingually. [6, 11]

Brand names
AVANZ Cupressus
Other names
Cupressus arizonica pollen extractArizona cypress pollen extractCupressus arizonica allergen extract
02

Targets

IgE (Immunoglobulin E)

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