Drug intelligence / Profile preview

Curcuma xanthorrhiza oil

Development stage
Preclinical
Modality
Small Molecules, Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Topical, Oral
01

Overview

Curcuma xanthorrhiza oil is an essential (volatile) oil extracted from the rhizome of Curcuma xanthorrhiza, a plant in the ginger family commonly known as Javanese turmeric. The principal active components are sesquiterpenes (notably 44.5% xanthorrhizol), ar-curcumene, β-curcumene, and a small amount of camphor; it also contains 1–2% curcuminoids such as curcumin[1][5][6]. The main pharmacological activities attributed to this extract include anti-inflammatory, antioxidant, anticancer, hepatoprotective, nephroprotective, antimicrobial (antibacterial and antifungal), antihypertensive, antirheumatic, diuretic and cholagogic effects[1][2][4]. Mechanistically these effects are linked to inhibition of inflammatory mediators (e.g., via diarylheptanoids/curcuminoids), upregulation of tumor suppressor proteins like p53 by xanthorrhizol for anticancer activity[4], and increased bile secretion due to d-camphor content[1][2]. It is used primarily in skincare preparations but also appears in traditional medicine for digestive disorders and liver protection[3][7].

Brand names
temu lawak oil
Other names
javanese turmeric oilcurcuma xanthorrhiza volatile oil
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ABCC2 (ATP-binding cassette sub-family C member 2)NOS2 (Nitric Oxide Synthase 2)TP53 (Cellular Tumor Antigen p53 R175H)

Beyond the preview

Go deeper on Curcuma xanthorrhiza oil.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Curcuma xanthorrhiza oil.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call