Drug intelligence / Profile preview

CUT-02

Development stage
Unknown
Lead developer
Hypothesis
Modality
Recombinant Proteins and Enzymes
Administration
Topical
01

Overview

CUT-02 is a patented, proprietary precision endolysin enzyme developed by Hypothesis for the treatment of acne vulgaris. Unlike conventional broad-spectrum acne treatments (such as benzoyl peroxide or topical antibiotics) that indiscriminately eliminate both harmful and beneficial skin bacteria, CUT-02 is engineered to selectively target and degrade the cell walls of Cutibacterium acnes (C. acnes) without disrupting the surrounding skin microbiome. By preserving beneficial skin flora, CUT-02 helps restore long-term microbiome balance and reduces acne-associated inflammation, redness, and breakouts. It is formulated as the active component in topical skincare products, including serums, clarifying sprays, and microdart blemish patches, offering a highly tolerated, non-irritating alternative to traditional therapies.

Other names
CUT-02 endolysinCUT02 endolysinCUT 02 endolysinCUT-02 enzymeCUT02 enzymeCUT 02 enzymeCUT-02 lysinCUT02 lysinCUT 02 lysin

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