Drug intelligence / Profile preview

CVD-1301.V01

Development stage
Phase 2
Lead developer
Hangzhou Converd
Modality
Oncolytic Viruses → Oncolytic Therapeutics
Administration
Intratumoral
01

Overview

CVD-1301.V01 (hV01) is an oncolytic virus therapy developed by Hangzhou Converd Co., Ltd. It is a recombinant human IL-21-expressing oncolytic vaccinia virus designed to target IL-21R (Interleukin 21 Receptor) as an agonist. The drug works through an IL-21R agonist mechanism, which may enhance anti-tumor immune responses. It is being investigated for the treatment of advanced malignant solid tumors and has shown clinical activity in patients who have failed standard treatments.

Other names
Recombinant human IL-21-expressing Oncolytic Vaccinia Virus
02

Targets

IL21R (Interleukin-21 receptor)

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