Drug intelligence / Profile preview

CVXL-0069

Development stage
Preclinical
Lead developer
CleveXel Pharma
Modality
Small Molecules
01

Overview

CVXL-0069 is a small molecule dual modulator of the adenosine A1 and A2A receptors, currently being developed by CleveXel Pharma. The program is in the IND-enabling stage, preparing for clinical entry. Adenosine receptors are G protein-coupled receptors (GPCRs) that mediate the effects of extracellular adenosine, influencing diverse biological systems including the central nervous system, cardiovascular system, and immune response. While CleveXel has not specified the primary therapeutic indication for CVXL-0069, compounds targeting these receptors are frequently investigated for potential applications in neurodegenerative diseases, pain management, or inflammatory disorders.

02

Targets

ADORA2A (Adenosine A₂A Receptor)ADORA1 (Adenosine receptor A1 subtype)

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