cx-614

CX-614 is a small molecule positive allosteric modulator of AMPA receptors (an AMPAkine). It enhances synaptic transmission by slowing deactivation and desensitization of the AMPA receptor channel. This compound is primarily used in research settings to study cognitive enhancement and neuroprotection. Its mechanism involves binding to an allosteric site on the AMPA receptor complex (subsite A), thereby potentiating glutamatergic neurotransmission. There are no approved therapeutic indications for CX-614; it is not marketed as a pharmaceutical drug but is available for laboratory research use only[8].

Other names

2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one2H-Pyrazolo[4,3-c]pyridine87V631480WMFCD13248581MFCD-13248581MFCD 13248581CAS 191744-13-5CAS191744-13-5CAS-191744-13-5UNII 87V631480WUNII87V631480WUNII-87V631480W