Drug intelligence / Profile preview

CX15

Development stage
Preclinical
Lead developer
Hangzhou Bangshun Pharmaceutical
Modality
Molecular Glues → Targeted Protein Degraders (TPDs) → Small Molecules
Administration
Oral
01

Overview

CX15 is a preclinical-stage small molecule molecular glue developed by Hangzhou Bangshun Pharmaceutical (Biosun Pharma). It is designed to target Kelch-like ECH-associated protein 1 (KEAP1), a key regulator of the NRF2 signaling pathway often implicated in cancer progression and resistance. The drug is being developed for the treatment of solid tumors, with potential applications as both a monotherapy and in combination regimens. Hangzhou Bangshun Pharmaceutical expects to submit an Investigational New Drug (IND) application for CX15 in 2027.

Other names
CX15 (Molecular Glue)
02

Targets

KEAP1 (Kelch-like ECH-associated protein 1)

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