Drug intelligence / Profile preview

CXF11

Development stage
Unknown
Lead developer
Chance Pharmaceuticals
Modality
Small Molecules
Administration
Inhalation
01

Overview

CXF11 is an inhaled tiotropium bromide product developed by Chance Pharmaceuticals for maintenance treatment of chronic obstructive pulmonary disease, specifically the prevention of bronchospasm in adults with COPD. Tiotropium bromide is a long-acting muscarinic antagonist small molecule bronchodilator that blocks airway muscarinic acetylcholine receptors, thereby reducing cholinergic bronchoconstriction and promoting sustained bronchodilation. Based on the provided context, CXF11 uses Chance Pharmaceuticals' proprietary inhaler device with improved usability and visual design relative to reference products, and its China marketing application was accepted after successful bioequivalence and stability studies, consistent with development of a tiotropium bromide generic or reference-comparable inhalation product.

Other names
tiotropium bromide inhalation drug
02

Targets

M1 (Muscarinic acetylcholine receptor M1)CHRM3 (M3)CHRM2 (M2)

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