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CXG90 is a small molecule drug under preclinical development by Hangzhou Chance Pharmaceuticals. It acts as a multi-target agent with three distinct mechanisms of action: - Glucocorticoid receptor (GR) modulator - Muscarinic acetylcholine receptor (mAChR) antagonist - Beta-2 adrenergic receptor (β2-adrenergic receptor) agonist The drug is being developed primarily for immune system and respiratory diseases, with active indications including asthma and chronic obstructive pulmonary disease (COPD). Its multi-modal mechanism suggests potential for both anti-inflammatory effects and bronchodilation[1].
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