Drug intelligence / Profile preview

CY006

Development stage
Preclinical
Lead developer
Shanghai Chaoyang Pharmaceutical
Modality
Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

CY006 is an experimental degrader antibody conjugate (DAC) being developed by Shanghai Helioson Pharmaceutical for the potential treatment of tumors and autoimmune diseases. Utilizing a protein homeostasis platform, CY006 consists of a targeting monoclonal antibody conjugated to a degrader payload, such as a PROTAC or molecular glue. This approach aims to combine the high specificity of antibodies with the potent protein-degradation capabilities of targeted protein degraders to address previously 'undruggable' targets. The candidate is currently in the discovery or early preclinical stage of development.

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