cyanobacterial extract L30-O

Cyanobacterial extract L30-O is a research-stage organic extract derived from the *Nostoc* cyanobacterial strain 113.5, which was originally isolated from the lichen *Nephroma arcticum* in Finland. Identified in a 2014 academic screening study, the extract demonstrates potent apoptosis-inducing activity against acute myeloid leukemia (AML) cells, including the rat IPC-81 and human Molm-13 cell lines. Notably, L30-O has shown the ability to partially overcome chemoresistance associated with the overexpression of the anti-apoptotic protein Bcl-2. As a crude natural product extract, its specific active chemical constituents have not yet been purified or characterized, and it has not progressed into formal clinical development.

Other names

Nostoc strain 113.5 organic extract