Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
CybroCell
- Development stage
- Unknown
- Lead developer
- FibroBiologics
- Modality
- Cell Therapies
- Administration
- Intradiscal Injections
01
Overview
CybroCell is a fibroblast-based cell therapy developed by FibroBiologics. It is specifically being developed for the treatment of degenerative disc disease (DDD). This investigational therapy utilizes allogeneic human dermal fibroblasts (HDFs) delivered via intradiscal injections. Preclinical and early clinical data suggest that CybroCell can initiate a regenerative process in the intervertebral discs, leading to increased regeneration, disc height, and expression of structural genes like collagen type I and II, as well as proteoglycan content. This mechanism aims to reduce pain and improve back mobility in patients suffering from DDD. Fibroblasts also contribute to immune modulation and tissue remodeling.
- Brand names
- CybroCell
- Other names
- allogeneic fibroblast therapyfibroblast cell therapy
02
Targets
TGFB1 (Transforming growth factor Beta-1 proprotein)
Beyond the preview
Go deeper on CybroCell.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on CybroCell.