cyclacillin

Cyclacillin is a semisynthetic aminopenicillin antibiotic and a cyclohexylamido analog of penicillanic acid. It was developed as an orally active penicillin with improved absorption and greater resistance to beta-lactamase hydrolysis compared to ampicillin. Its primary mechanism of action is the inhibition of bacterial cell wall synthesis through binding to penicillin-binding protein (PBP), resulting in bactericidal activity. Cyclacillin was used for the treatment of bacterial infections caused by susceptible organisms, including both gram-positive and some gram-negative bacteria. It has largely been replaced by newer penicillins due to advances in antibiotic therapy[1][2][3][4][5].

Brand names

CyclapenCyclapen-WVastcillin

Other names

ciclacillin