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cyclophosphamide + doxorubicin + paclitaxel
- Development stage
- Phase 4
- Lead developer
- Baxter
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
A chemotherapy combination regimen consisting of cyclophosphamide, doxorubicin (also known as Adriamycin), and paclitaxel. This regimen is typically administered sequentially, with cyclophosphamide and doxorubicin (AC) given first, followed by paclitaxel. It is primarily used in the treatment of breast cancer in both adjuvant and neoadjuvant settings. The regimen can be administered in standard 3-week cycles or dose-dense 2-week cycles with growth factor support.
- Brand names
- Taxol (paclitaxel)Adriamycin (doxorubicin)Cytoxan (cyclophosphamide)
- Other names
- AC-paclitaxelAC followed by paclitaxelAC-T
02
Targets
DNAMicrotubuleTOP2A (DNA topoisomerase II)
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