Drug intelligence / Profile preview

cyclophosphamide + doxorubicin + paclitaxel + pazopanib

Development stage
Unknown
Lead developer
Novartis
Modality
Small Molecules
Administration
Intravenous, Oral
01

Overview

This is a combination of four anticancer drugs. The first three (cyclophosphamide + doxorubicin + paclitaxel) are commonly used together in breast cancer treatment, typically with doxorubicin and cyclophosphamide (AC) administered first, followed by paclitaxel. Pazopanib is a tyrosine kinase inhibitor primarily used for renal cell carcinoma and soft tissue sarcomas. This specific four-drug combination does not appear to be a standard regimen in clinical practice based on the available information.

02

Targets

VEGFR2 (Vascular endothelial growth factor receptor 2)TUBB (Tubulin (alpha and beta subunits))DNATOP2A (DNA topoisomerase II)PDGFR (PDGFR family)

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