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A chemotherapy combination regimen consisting of cyclophosphamide, 5-fluorouracil, and vinorelbine used primarily for the treatment of locally advanced or metastatic breast cancer. This combination has shown efficacy comparable to anthracycline-containing regimens while maintaining a manageable toxicity profile, making it suitable for patients who have been extensively exposed to anthracyclines during adjuvant therapy or who have contraindications to their use.
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