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cyclosporine + gabapentin
- Development stage
- Unknown
- Lead developer
- Tigercat Pharma
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
A combination of cyclosporine, an immunosuppressant medication used to prevent organ rejection in transplant patients and treat autoimmune conditions, and gabapentin, an anticonvulsant medication used to treat neuropathic pain, partial-onset seizures, and restless legs syndrome. The therapeutic efficacy of gabapentin may be decreased when used in combination with cyclosporine.
02
Targets
Cyp (Cyclophilin family)CACNA2D1 (Voltage-gated calcium channel subunit alpha2/delta-1)α2δ (Voltage-gated calcium channel alpha-2-delta subunit)ADORA1 (Adenosine receptor A1 subtype)GABA-B (Gamma-aminobutyric acid receptor type B)KCNQ3 (Potassium voltage-gated channel subfamily Q member 3)KCNQ5 (Potassium voltage-gated channel subfamily KQT member 5)CACNA1B (Voltage-dependent N-type calcium channel subunit alpha-1B)
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