Drug intelligence / Profile preview

Cyclosporine A, Esomeprazole, and Sodium Hyaluronate

Development stage
Unknown
Lead developer
Semmelweis University
Administration
Oral, Ophthalmic, Topical
01

Overview

The combination of cyclosporine A, esomeprazole, and sodium hyaluronate is not identified as a single formulated product in the provided search results. Instead, these are three distinct medications with individual uses and known interactions. Cyclosporine A is an immunosuppressant used for various conditions including organ transplant rejection prevention, autoimmune disorders, and dry eye disease. Esomeprazole is a proton pump inhibitor used to reduce stomach acid. Sodium hyaluronate is often used in eye drops for dry eye conditions. While studies investigate the combined use of cyclosporine A and sodium hyaluronate specifically for treating dry eye syndrome and post-refractive surgery dry eye disease, and a documented drug interaction exists between cyclosporine and esomeprazole (where esomeprazole can increase the serum concentration of cyclosporine), there is no information about a single formulated product containing all three components together.

02

Targets

Cyp (Cyclophilin family)FPR1 (Formyl peptide receptor 1)ATP4A (Potassium–transporting ATPase alpha chain 1)CN (Calcineurin)

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