cyclosporine vehicle

Cyclosporine vehicle is the placebo control formulation used by Allergan in clinical trials, specifically Phase 3 study NCT00884585, to evaluate the efficacy and safety of cyclosporine 0.010% ophthalmic solution for the treatment of atopic keratoconjunctivitis (AKC). The vehicle contains the same inactive ingredients as the active drug product—typically including components to maintain stability, tonicity, and pH—but lacks the active immunosuppressive agent cyclosporine. AKC is a chronic, severe inflammatory condition of the eye, and the vehicle serves as a comparator to distinguish the pharmacological action of cyclosporine from the potential lubricating effects of the eye drop base.

Other names

cyclosporine vehicle-Allergan-atopic keratoconjunctivitisCyclosporine Vehicle