cymarin

Cymarin is a cardiac glycoside belonging to the class of cardenolide glycosides and derivatives. It is found in plants such as *Apocynum cannabinum* and *Apocynum venetum*. Cymarin acts by inhibiting the Na+/K+-ATPase pump, leading to increased intracellular calcium concentration, which enhances myocardial contractility (positive inotropic effect) and slows heart rate (negative chronotropic effect). It has been used historically as a cardiotonic agent for conditions like heart failure and arrhythmias. Recent research also suggests potential antitumor activity against breast cancer and pancreatic cancer, as well as antifeedant effects in agriculture[2][3][4].

Other names

CymarineStropheantin KStrofantidina cimarosideTsimarinZimarin