Drug intelligence / Profile preview

Cymbopogon citratus extract

Development stage
Preclinical
Administration
Oral, Topical
01

Overview

Cymbopogon citratus extract is a natural product derived from the lemongrass plant, *Cymbopogon citratus*. It is rich in various phytochemicals, including essential oils (such as citral, myrcene, geraniol, and citronellal), flavonoids (like luteolin, quercetin, kaempferol, and apigenin), and phenolic compounds. This extract exhibits a broad spectrum of pharmacological activities, including antioxidant, anti-inflammatory, antimicrobial (antibacterial, antifungal, antiamoebic, antiprotozoal), antidiarrheal, antifilarial, antimalarial, antimutagenic, antimycobacterial, hypoglycemic, hypolipidemic, analgesic, antipyretic, and potential anticancer effects. Its mechanisms of action involve modulating cellular pathways, inducing apoptosis in cancer cells, acting as a calcium antagonist, and influencing various receptor systems. Traditionally, it has been used for gastrointestinal discomforts, pain relief, infections, and as a stimulant. It is commonly consumed as a tea, used as a flavoring agent, and applied topically in various preparations.

Other names
Lemongrass extractCymbopogon citratus
02

Targets

26S proteasomeCHRM4 (M4)M1 (Muscarinic acetylcholine receptor M1)CHRM2 (M2)MAOB (Monoamine oxidase B)

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