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CZ-1408 is an investigational oxalate-degrading enzyme under clinical development by Oxidien Pharmaceuticals. It is being developed for the treatment of secondary and enteric hyperoxaluria. The drug originated from the enzyme intellectual property of Captozyme, a company that previously focused on developing oxalate-degrading enzymes, such as Nephure, to assist individuals in managing low-oxalate diets for conditions like kidney stones.
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