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D-D3

Development stage: Preclinical
Modality: Monoclonal Antibodies → Antibody-Based Therapeutics

Overview

D-D3 is a biotinylated monoclonal antibody designed to target Pro-gastrin releasing peptide (ProGRP), specifically the ProGRP(31-98) fragment. It is being investigated for its role in a pretargeting procedure for the early diagnosis of small cell lung cancer (SCLC) through radioimmunoimaging, demonstrating selective accumulation in SCLC xenografts in preclinical models.

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