d-mannose + proanthocyanidins

**d-mannose + proanthocyanidins** is a combination dietary supplement widely used to support urinary tract health, particularly as an adjunct or alternative to antibiotics in preventing and managing uncomplicated urinary tract infections (UTIs), especially in women[3][5]. - **D-mannose** is a naturally occurring monosaccharide that is rapidly absorbed and excreted in the urine, where it can bind to E. coli and other uropathogens, helping to prevent their adhesion to the urothelium and aiding in their removal from the urinary tract[1][3]. - **Proanthocyanidins** are polyphenolic compounds, commonly extracted from cranberry, that exhibit potent antioxidant properties and may prevent bacterial adhesion (notably by inhibiting P-fimbriae-mediated attachment of E. coli), as well as modulate inflammatory pathways[3][2][5]. - Clinical studies indicate that the combination promotes higher cure rates and lower recurrence of uncomplicated UTIs, including in cases of antibiotic-resistant bacteria[3]. - The product is used orally, primarily as a dietary supplement, not as a pharmaceutical drug[1][5].

Brand names

TheraCran Max

Other names

cranberry extract + d-mannosecranberry & mannosecranberry mannose