Drug intelligence / Profile preview

D-Myo-Inositol-Hexasulphate

Development stage
Unknown
Modality
Small Molecules
01

Overview

D-Myo-Inositol-Hexasulphate is a synthetic, highly sulfated derivative of myo-inositol, structurally related to inositol phosphates such as inositol hexaphosphate (IP6/phytic acid). It is a small molecule with the formula C6H12O24S6 and a molecular weight of approximately 660.5 g/mol[3][6]. While naturally occurring in plants and mammalian cells as phosphorylated forms (notably IP6), the sulfated form is primarily experimental. The compound acts as a strong chelator of minerals and may influence cellular signaling pathways by mimicking or interfering with endogenous inositols. There are no approved therapeutic indications for this compound; it has not advanced beyond experimental status[3]. Its mechanism of action likely involves modulation of cellular processes through interaction with proteins that bind poly-anionic molecules, but specific pharmacological targets have not been established.

Other names
D-MYO-INOSITOL-HEXASULPHATEInositol hexasulfate23330-83-8CHEMBL3945401CHEMBL-3945401CHEMBL 3945401
02

Targets

p47phox PX domain (NCF1 PX domain)CYP1A (Cytochrome P450 family 1 subfamily A)

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