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Daktavira
- Development stage
- Unknown
- Lead developer
- European Egyptian Pharmaceutical Industries
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Daktavira is a generic formulation of daclatasvir, a small molecule inhibitor of the hepatitis C virus (HCV) nonstructural protein 5A (NS5A) replication complex. Developed and manufactured by European Egyptian Pharmaceutical Industries (EEPI) and studied by the Genuine Research Center in Egypt, it is used for the treatment of chronic hepatitis C virus infection. Daclatasvir exhibits pan-genotypic antiviral activity by binding to the N-terminus of NS5A, thereby inhibiting both viral RNA replication and virion assembly. In Egypt, Daktavira has been utilized in national treatment programs, typically in combination with sofosbuvir, with or without ribavirin, particularly for patients with HCV genotype 4.
- Brand names
- Daktavira
- Other names
- daclatasvir
02
Targets
NS5A (Hepatitis C virus nonstructural protein 5A (genotype 1b))
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