Dalian Medical Univ. JAK3 compound 7n

Dalian Medical Univ. JAK3 compound 7n: sourced facts only. name: "Among them, 7n, a promising compound, exhibited a strong combining capability with JAK3 (half-maximal inhibitory concentration [IC50] = 0.7473 nM) and effective antiproliferative activities against Bortezomib-resistant KM3 cells (IC50 = 0.2452 μM)." [PMID:41895096]; target: "Among them, 7n, a promising compound, exhibited a strong combining capability with JAK3 (half-maximal inhibitory concentration [IC50] = 0.7473 nM) and effective antiproliferative activities against Bortezomib-resistant KM3 cells (IC50 = 0.2452 μM)." [PMID:41895096]; developer: "College of Pharmacy, College of Medical Laboratory, College of Basic Medical Sciences, Dalian Medical University, Dalian, 116044, PR China; School of Science, Westlake University, Hangzhou, 310030, PR China." [PMID:41895096]; stage: "Furthermore, 7n showed notable inhibition of tumor growth in a murine Bortezomib-resistant KM3 cell xenograft model." [PMID:41895096]