dalosirvat

Dalosirvat (SM04554) is an investigational small molecule drug developed as a topical solution for the treatment of androgenetic alopecia (AGA), the most common form of hair loss in men and women. It acts as a Wnt pathway activator, modulating this signaling pathway to stimulate hair follicle regeneration and promote hair growth. The Wnt pathway is crucial for cell growth, migration, and tissue repair. Preclinical studies demonstrated that SM04554 increased Wnt signaling and accelerated the transition from telogen to anagen phase in hair follicles, resulting in increased hair growth. Clinical trials have shown that topical application of SM04554 increases non-vellus (thicker) hair counts with a favorable safety profile[1][2][3][6].

Other names

dalosirvat