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dAMD-1 is a preclinical drug candidate being developed by **insitro** for the treatment of dry age-related macular degeneration (dAMD). Discovered using insitro's proprietary machine learning-driven platform, the asset was identified by integrating high-content cellular data with human genetics to model disease states in vitro, specifically utilizing iPSC-derived retinal pigment epithelium (RPE) cells. The program aims to address the underlying biological drivers of geographic atrophy and vision loss associated with dAMD. As of early 2024, specific details regarding the molecular target, therapeutic modality, and route of administration remain proprietary and have not been publicly disclosed.
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