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dAMD-3 is a preclinical therapeutic candidate being developed by insitro for the treatment of dry age-related macular degeneration (dAMD). The asset was identified using insitro's proprietary discovery platform, which integrates machine learning, human genetics, and high-content cellular data to uncover novel disease drivers. As part of insitro's ophthalmology pipeline, dAMD-3 is aimed at addressing the underlying biological mechanisms of retinal degeneration and geographic atrophy. While the specific molecular target and modality have not been publicly disclosed, the program represents the company's application of its 'insitro-readout' (ISRO) approach to complex ocular diseases.
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