Drug intelligence / Profile preview

dandelion

Development stage
Approved
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Dandelion (Taraxacum officinale) is a perennial herb native to Europe and now widespread globally. All parts of the plant—leaf (folium), root (radix), and flower—are used in traditional medicine. Dandelion is rich in vitamins A,C,D,B complex and minerals such as iron,potassium,and calcium[7][8]. Traditionally it has been used for digestive disorders (as a bitter tonic), liver and gallbladder support/detoxification,[6][7][9] mild diuretic effects,[5][8] appetite stimulation,[5] anti-inflammatory activity,[4][5], antioxidant properties[4][7], skin health[4], blood sugar regulation[7], cholesterol lowering[7], immune modulation/antimicrobial effects[4]. In vitro/in vivo studies suggest hepatoprotective,lipid-lowering,hypoglycemic,and anticancer activities; however robust clinical evidence in humans is lacking.[5] The German Commission E approves its use for dyspepsia,liver/gallbladder complaints,and urinary tract infections.[6] It is not FDA-approved as a drug; it is sold as an herbal supplement.

Brand names
TADIOS
Other names
Taraxacum officinaleBlowballCankerwortCochetCouronne de MoineDélice PrintanierDent-de-LionDiente de LeonDudalEndive SauvageFausse ChicoréeFlorin d'OrFlorion d'OrHerba TaraxaciLaitue de ChienLeontodon taraxacumLion's ToothPisse au LitPissenlitPriest's CrownPu Gong Ying (Chinese)Salade de TaupeTaraxaci HerbaTaraxacumTête de MoineWild Endive
02

Targets

ATP1A (Sodium/potassium-transporting ATPase)

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