danggui sini

Danggui Sini is a Traditional Chinese Medicine (TCM) formula, often administered as a granule or decoction, primarily used to treat conditions associated with Cold Coagulation and Blood Stasis in TCM theory. In modern clinical research, it is being investigated for its potential to prevent and treat oxaliplatin-induced peripheral neuropathy (OIPN) in patients with colorectal cancer. The formula typically consists of seven herbs: *Angelica sinensis* (Danggui), *Cinnamomum cassia* (Guizhi), *Paeonia lactiflora* (Shaoyao), *Asarum sieboldii* (Xixin), *Glycyrrhiza uralensis* (Gancao), *Tetrapanax papyrifer* (Tongcao), and *Ziziphus jujuba* (Dazao). Its mechanism is thought to involve anti-inflammatory, antioxidant, and neuroprotective effects, potentially by modulating neurotrophic factors and reducing oxidative stress in peripheral nerves.

Brand names

Treasure of the East Extract Granule FormulasGolden Needle Dang Gui Si Ni Tang Granules

Other names

Danggui Sini DecoctionDanggui Sini TangDGSNDDanggui Sini granule