Drug intelligence / Profile preview

danqi granules

Development stage
Unknown
Lead developer
Handan Pharmaceutical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Danqi Granules (丹杞颗粒) is a Traditional Chinese Medicine (TCM) product developed and manufactured by Handan Pharmaceutical. It is approved in China for the treatment of osteoporosis, specifically for patients presenting with kidney deficiency and blood stasis according to TCM diagnostic principles. The formulation is composed of several herbal extracts, including *Salvia miltiorrhiza* (Danshen), *Lycium barbarum* (Gouqizi), *Epimedium* (Yinyanghuo), and *Rehmannia glutinosa* (Shudihuang). These ingredients work synergistically to tonify the liver and kidney, strengthen bones, and promote blood circulation. Clinical use focuses on improving bone mineral density and relieving symptoms such as lower back pain and limb weakness associated with bone loss.

Brand names
Danqi Granules丹杞颗粒
Other names
Danqi Keli
02

Targets

IL-6 (Interleukin 6)VEGFA (Vascular endothelial growth factor A)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)TP53 (Cellular Tumor Antigen p53 R175H)CASP3 (Caspase-3)IL1B (Interleukin-1 beta)

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